melanoma

In metastatic melanoma a generalized darkening of the skin (diffuse melanosis cutis) may occur.Usually melanuria is also present.

转移性瘤患者可发生全身性皮肤变（皮肤播散性变），通常存在。

CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant surial adantage for patients with pulmonary metastatic melanoma.

其他鉴别风险因子算术控制后，转移瘤切除术对有肺转移性色瘤患者仍有显著生存优势。

Previous work from our laboratory reported that aggressive melanoma and breast carcinoma express the embryonic morphogen Nodal, which is essential for human embryonic stem cell (hESC) pluripotency.

然而，癌症相关环境缺乏合适调控机制来维持一个正常细胞表型。