Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究表明线粒氢酶是内催硝酸甘油生物转的主要途径，线粒氢酶同时有氢酶和酯酶的催活性，其酯酶活性可以通过将硝酸甘油硝形成一氧氮，进而血管扩张。