Shame can be crippling and debilitating.

羞愧会起到削弱作用。

Though temporary, opioid withdrawal can be incredibly debilitating.

阿片类药物戒断症状虽然短暂， 却能让人极度衰弱。

It can be debilitating, and cleaning won't solve the problem.

它是很累人的，清洁并没有办法解决问题的根源。

But he insisted Mr. Trump's behavior is more embarrassing for the country than debilitating to his efforts.

但他坚称，与妨碍疫苗工作相比，特朗普的行为更是令美国难堪。

For others, the effects may include debilitating cramps, bloating, migraines and depression.

对其他人来说，其影响可能包括使人虚弱的抽筋、腹胀、偏头痛和抑郁。

Four is absolutely excruciating the debilitating, incapacitating, just shut you down, just absolute sheer pain.

四级是绝对折磨人的，使人衰弱，丧失能力，让你晕厥，纯粹的痛苦。

That could then hit world markets dead on in ways that could really be debilitating.

这会给世界市场以致命一击，使世界市场更加脆弱。

Well, she does say that too much shame can be crippling and debilitating.

好吧，她确实说太多的羞愧会起到削弱作用。

But the noise of it has grown deafening and debilitating in the past two years.

但是在过去的两年里，恐惧之声变得震，令人衰弱。

And that is these debilitating medical ailments. They have become known as the Havana Syndrome.

就是那些使人衰弱的医疾病，众所周知的“哈瓦那综合症”。

Another study of Korean immigrants found the discrimination was linked to debilitating mental health effects.

另一个针对韩国移民的研究发现，歧视和削弱心理健康的影响有关。

I hear every day from Americans whose loved ones are suffering from addiction and other debilitating diseases.

我每天都从人们那里听到这些, 他们爱着的人们在忍受着药物上瘾, 其他人忍受着使人衰弱的疾病。

He suffered from epileptic convulsions along with a host of gastric diseases and debilitating migraine headaches.

他患有癫痫性抽搐，还有一系列胃病和使人衰弱的偏头痛。

And yet the U.S. market has offered no drug expressly designed to prevent these debilitating headaches.

尽管如此，美国市场还是没有专门用来预防这些令人难以承受的头痛的药物。

With yet more billions of years looming ahead they will be struck down with a debilitating ennui.

未来还有数十亿年要面对，这些永生者将会感到一种压倒一切的无聊感。

Consumers started calling out some very debilitating problems with the conventional construction of the American potato chip.

消费者开始指出美国薯片的传统结构存在一些非常严重的问题。

The ruling centred on two women with debilitating conditions, both of whom died before it was handed down.

该判决关注了两名身体衰弱的妇女，两人都在判决宣告之前死亡。

During heart attacks and other medical emergencies, people often die or sustain debilitating organ damage from oxygen deprivation.

在心脏病突发以及其他紧急医疗情况时，人们常因为缺氧而死亡或是器官受损。

On other occasions, though, autism manifests as part of a range of cognitive problems. Then, the condition is debilitating.

然而，另一些场合，自闭症表现为一系列认知问题的一部分。

So even though we might live longer, we do tend to suffer more for some of these debilitating conditions.

所以即使我们可能活得更长，但我们确实倾向于在这些使人衰弱的情况下遭受更多的痛苦。