Genetic testing for HLA-B27 can be done to help confirm the diagnosis.

检测到HLA-B27基因能够协助确诊。

Each of us have different HLA profiles. The study is elegant science.

我们每个人的HLA情况都不同。这项研究是优雅的科学。

A set of genes called HLA, for instance, are involved in running the immune system.

例如，一组被称为HLA的基因参与了系统的运行。

Turns out, these women also share a mutation in the gene called HLA-B27 that the others lack.

原来，这些女在HLA-B27基因上有突变，而别人没有。

Is that people who carry archaic HLAs could be more prone to autoimmunity.

携带过时HLAs的人可能更容易患上自身疾病。

There can be downsides to archaic HLAs.

可能有不利于过时的HLAs。

All right, as a quick recap, ankylosing spondylitis is an autoimmune process, associated with the HLA-B27 gene, which attacks vertebral joints.

好，简单回顾下：强柱炎是一种与HLA-B27基因有关的自身疾病，会柱关节受累。

Based on studying people with autoimmune hepatitis, they often have HLA-DR3 and -DR4, which are both MHC class II surface receptors.

基于对自肝病人的研究，他们（的体细胞表面）常常含有HLA-DR3和HLA-DR4，两者都是MHC-II类分子。

It says, the findings of these HLA alleles may have some practical implications as well.

它说, 这些HLA等位基因的发现也可能有一些实际意义。

This adaptive arm can recognise the signature of " selfness" provided by an individual's HLA proteins.

这种自适应臂可以识别个体 HLA 蛋白提供的“自我”特征。

Everyone's HLA profile is slightly different, and reveals which kinds of diseases we have immunity to.

每个人的 HLA 概况略有不同，揭示了我们对哪些疾病具有力。

HLA is a group of proteins that play a role in coding for some of our immune response.

HLA 是一组蛋白质， 在编码我们的某些反应中发挥作用。

In some studies, single people have been found to prefer the BO of HLA dissimilar individuals.

在一些研究中， 发现单身人士更喜欢 HLA 不同个体的 BO。

One really important group of genes involved in regulation of the immune response is the human leukocyte antigen system, or HLA system.

一组涉及调节反应的重要基因叫作人体白细胞抗原系统，或HLA系统。

Unlike with blood transplants, there are thousands of HLA types, and even siblings and close relatives may not have compatible bone marrow.

与输血不同HLA（人类白细胞抗原）有几千种，甚至患者与兄弟姐妹、近亲的HLA都不一定能相容。

Disrupting beta cells' HLA expression is not the only possible approach to deflecting the adaptive immune system.

破坏 β 细胞的 HLA 表达并不是转移适应系统的唯一可能方法。

Lack of HLA proteins does, however, bring a cell to the attention of immunity's other arm, the innate system.

然而，缺乏 HLA 蛋白确实会引起系统的另一个分支——先天系统的注意。

The first part of Dr Schrepfer's approach is therefore to prevent the production of HLA proteins in laboratory-grown beta cells destined for transplant.

因此，Schrepfer 博士方法的第一部分是阻止用于移植的实验室培养的 β 细胞中产生 HLA 蛋白。

However, the most comprehensive study of its kind found no link between BO preference, HLA dissimilarity and chosen partners in 3,700 married couples.

然而， 同类研究中最全面的研究发现，在 3, 700 对已婚夫妇中， BO 偏好、 HLA 差异与选择的伴侣之间没有联系。

The archaic HLAs may interact more poorly with some of these proteins potentially causing mistakes like autoimmunity and I've got a quote at the end.

古老的HLAs可能与其中一些蛋白质的相互作用更差, 可能会自身等错误, 我在最后引用了一句话。