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Histones are characterized by numerous posttranslational modifications that influence gene transcription.

组蛋的特点是大量的翻译后修饰,这些修饰可以影响基因转录。

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The proteins that combine with DNA are generally of characteristic types called histones and protamines.

与去氧核糖核酸结常属于被称为组蛋或鱼精蛋的特殊

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Each long strand of DNA combines with histones and nonhistone proteins to make up the substance chromatin.

个长链DNA与组蛋和非组蛋一起构成染色质物质。

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The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other,which are histone transacetylase and histone deacetylase.

组蛋乙酰化和去乙酰化由一对功能相互拮抗的蛋酶——组蛋乙酰基转移酶和组蛋去乙酰化酶负责。

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Chromatin The loose network of threads seen in nondividing nuclei that represents the chromosomal material, consisting of DNA, protein (mainly histone), and small amounts of RNA.

间期细胞内由DNA,蛋质(主要是组蛋),以及少量的RNA组成的线性复结构,是间期细胞遗传物质存在的形式。

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But which histones unravel when depends on various influences.

但哪些组蛋白在什么时候分解取决于各种影响。

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科普

Think of how thread is wrapped around spool, that's kind of what histones look like.

想想线是如何缠绕到线轴的,就是组蛋白的子。

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DNA is wound around proteins called histones, which enable cells to pack large amounts of DNA into our nucleus.

DNA 被缠绕在组蛋白上,就能把大量 DNA 塞进细核里。

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科普

When DNA needs to be translated to make proteins, these histones unravel to let out a little bit of DNA at a time.

当DNA需要转换来制造蛋白质时,些组蛋白会在每次分散时分解出一点点DNA。

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So, in addition to histone and DNA, you also have epigenetic markers.

所以,除了组蛋白和 DNA, 你还有表观遗传标记。

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DNA tightly around a long filament of protein called histone. Coiling the molecule into a spring like that compresses it down.

DNA 紧紧围绕着称为组蛋白的蛋白质长丝。像分子盘绕成弹簧其压缩。

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These machines are called chromatin remodelers, and the way they work is that they basically scoot the DNA around these histones and they allow new pieces of DNA to become exposed.

些“机器”被称为染色质重塑器,它们载着 DNA在组蛋白上移动,让新的 DNA 片段暴露出来。

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But it also introduces a new problem: your DNA is wrapped SO tightly around the histone that your cell can’t access most of your genetic information anymore.

但它也引入了一个新问题:你的 DNA 被组蛋白包裹得如此紧密,以至于你的细无法再访问你的大部分遗传信息。

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科普

Your DNA is made up of two strains that wrap around each other in the famous double helix structure, to get even more compact and tiny, that DNA is wrapped around little proteins called histones.

你的DNA是由两个菌株组成的,它们以著名的双螺旋结构相互缠绕,变得更加紧密和微,DNA被包裹在称为组蛋白的蛋白质上。

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