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Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

酯评估研究表明在心力衰竭治中加用醛甾酮拮抗药可使总死低30%。

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Osmosis-心血管

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

另一个例子是肿瘤的生也会产生过多的醛固酮,一种类似于肾素的物质,会导致液体的积存。

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High aldosterone is associated with increased inflammation, Chronic kidney disease, Osteoporosis, and cardiovascular disease.

高醛固酮会增加体内炎症,导致慢性肾病、骨质疏松症以及心血管疾病。

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This suggests that people actually following the WHO guidelines are chronically raising their aldosterone.

也就是说,遵循世卫组织关于盐摄入量建议的人们,他们体内的醛固酮期处于较高

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Osmosis-泌尿

Now, an important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

所以,肾脏中有一种重要的激素可以帮助调节钾的重吸收和分泌,这就是醛固酮。

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Aldosterone has it's purpose, but it's not a hormone you want to regularly have high levels of.

醛固酮有其作用,但在人体中,这种荷尔蒙的能太高。

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Osmosis-内分泌

Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

醛固酮属于一特定激素家族或激素轴的一部分,这些激素共同作用,被称为肾素-血管紧张素-醛固酮系统。

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Osmosis-泌尿

An important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

肾脏中一种帮助调节钾重吸收或分泌的重要激素叫醛固酮。

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But, as I mentioned earlier, this renin angiotensin aldosterone system is stimulated by low salt intake.

但是,正如我之前提到的,低盐饮食会导致 RAA 系统活跃。

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Osmosis-内分泌

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

醛固酮增多症的诊断主要通过测定肾素与醛固酮的来完成。

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Osmosis-内分泌

Less aldosterone floating around in the blood causes the body to start dumping sodium from the blood into the urine.

血中醛固酮减少使得尿钠排出增多。

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Osmosis-内分泌

So in this case aldosterone levels are high and renin levels are low in.

因此,在这种情况下,醛固酮较高,肾素较低。

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As this study shows, a low salt diet increases aldosterone by more than 3 fold in healthy people.

这项研究显,健康正常人采用低盐饮食,其体内醛固酮将增加 3 倍有余。

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Osmosis-内分泌

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

醛固酮增多症的继发性原因通常是由于高肾素导致醛固酮生成过多。

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Osmosis-内分泌

This taking up more space issue triggers another mechanism in our body that causes the hormone aldosterone to stop being released.

血管容量的增加触发另一机制造成醛固酮这一激素停止释放。

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Osmosis-泌尿

Other pathological conditions that cause increased aldosterone levels include compensated heart failure and cirrhosis.

其他导致醛固酮增加的病理状况包括代偿期心衰和肝硬化。

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Osmosis-内分泌

With these medications around, aldosterone can't exert its effects.

有了这些药物,醛固酮就无法发挥其作用了。

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These drugs inhibit Angiotensin Converting Enzyme, hindering an important step in the RAA system resulting in lower aldosterone and lower blood pressure.

这种药物通过抑制血管紧张素转化酶的作用(RAA 系统的关键作用之一),以达到降低醛固酮及血压的目的。

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On the flip side of aldosterone, there is a group of hormones called natriuretic hormones, i. e. sodium urinating hormones.

在醛固酮的另一面,有一组激素叫利钠激素,也就是钠尿荷尔蒙。

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Another study shows that when salt intake drops below 1.5 teaspoons per day, a significant increase in renin and aldosterone occurs.

另一项研究显,当盐摄入量降至每天 1.5 茶匙以下,人体中的醛固酮及肾素将大幅上升。

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Osmosis-内分泌

Hyperaldosteronism can happen due to primary causes which is where the adrenal gland itself is responsible for the excess production of aldosterone.

醛固酮增多症可以是原发性的,即肾上腺本身产生了过量的醛固酮。

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