OBJECTIVE To synthesize the presumable bone-targeting nonsteroidal anti-inflammatory agents.METHODS L-Asp6 was prepared by aspartic acid which was protected.

目合成可能具有骨靶向非甾体抗炎药。

PASP-PEG block structure copolymer,comb shaped PASP-PEG block structure copolymer,aspartic acid and glycine,glutamic acid or propalanine copolymer are prepared.

还可以对聚天冬酸侧链进行改,引入烷基或烯烃基、基酸酯、磺酸基等功能基团,使其得到更广泛用。

Aspartic acid An AMINO ACID formed by transamination, in which the amino group of dlutamic acid is transferred to oxaloacetic acid.

由转基作用形成一种基酸，谷酸基基团被转移到草酰乙酸中。

The tripeptide Arginyl-Glycyl-Aspartic acid (RGD) is a common cell recognition site of many adhesive proteins contained in extracellular matrices and in the blood .

RGD三肽（精酰-甘酰-天冬酸）序列是细胞外基质及血液中许多粘附蛋白共有细胞识别位点。