While investigating Pd-catalyzed cross-coupling reactions between alkenyl halides and azides to yield vinyl azides, 1 H -1,2,3-triazoles were obtained as the main product.
Copper ions are frequently poisonous to biological systems.So Dr Bertozzi decided to work on a way to make azides and alkynes react without their involvement.
还原是向有机分子中引入氨基的重
方法。
交叉偶联反应之间烯卤
量叠叠,1小时-1,2,3-三唑为
，
最易爆炸的人造化合
讲，叠氮化
和炔
就像一个扣在一起的两半。
。
此，Bertozzi 博士决定研究一种方法，使叠氮化
