Lumbar puncture is classified as a relative contraindication in individuals with suspected increased intracranial pressure due to possible herniations.

腰椎穿刺，对于疑似因脑疝引起颅内压增高的患者，是种相对禁忌症。

There would be a contraindication if a perfect being did exist and we denied that such a being was omnipotent.

如果完美的存在确实存在，有禁忌症，而我们否认这样的存在是全能的。

Second-line immunotherapy Immunotherapy can still be used as second-line treatment in patients who were managed cautiously in the frst-line setting because of a relative contraindication to immunotherapy or poor PS at that time.

二线免疫治疗 对于因免疫治疗相对禁忌症或当时 PS 较差而在线环境中谨慎处理的患者，免疫治疗仍可用作二线治疗。

First-line chemotherapy alone For patients who have relative contraindications to upfront immunotherapy or PS worse than 1, a histology-appropriate platinum- doublet chemotherapy may be used (see above), with or without bevacizumab added for those with non-squamous histology.

仅线化疗 对于前期免疫治疗有相对禁忌症或 PS 低于 1 的患者，可以使用适合组织学的铂类双药化疗（见上文），对于非鳞状组织学的患者，可加用或不加用贝伐珠单抗。