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Testicular allotransplantation is one of the effective options for the treatment of male infertility and hypogonadism.

丸移植是治疗男性不育或性腺功能减退的有效

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Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

法利用亲属丸作供行同种丸移植4例,其中医源性无症2例,原发性性腺机能低下2例,术后观察患者血清酮水平、第二性征变化及性功能情况

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Osmosis-生殖

Next, endocrine dysfunctions that causes testosterone levels to fall, like hypogonadism, can cause erectile dysfunction.

其次,内分泌功能障碍导致睾酮水平下降,如功能减退会导致勃起功能障碍。

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Osmosis-内分泌

Some acquired causes of primary hypogonadism are radiation therapy, chemotherapy, and trauma to the gonads.

可引起原功能减退症因素有放疗、化疗和腺创伤。

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Osmosis-内分泌

Some congenital causes of primary hypogonadism are genetic diseases like Klinefelter or Turner syndrome.

可引起原功能减退的先天因素包括Klinefelter合征或Turner合征等遗传病。

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Osmosis-遗传

These streak ovaries can't produce sex hormones, resulting in hypogonadism and low estrogen levels.

条索状卵巢无法产生激素,导致功能低下、雌激素水平低。

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Osmosis-内分泌

Some acquired causes are similar to primary hypogonadism, radiation therapy, chemotherapy, and trauma to the gonads.

因素与原功能减退症相似,也包括放疗、化疗和腺创伤。

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Osmosis-内分泌

Because of this, Kallmann syndrome is a type of hypogonadotropic hypogonadism disorder.

正因如此,Kallmann合征是一种低促腺激素腺功能减退症。

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Osmosis-内分泌

There are two main causes of hypogonadism.

功能减退有两个主要病因

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Osmosis-内分泌

Blood tests of hormone levels can give an idea of the type of hypogonadism.

血液激素水平的检测可以为功能减退的类型提供参考

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Osmosis-内分泌

So, to recap: Kallmann syndrome is a type of hypogonadotropic hypogonadism where olfactory neurons and gonadotropin-releasing hormone neurons don't function normally.

Kallmann合征是一种低促腺激素功能减退症,其嗅觉神经元与促腺激素释放激素神经元不能挥正常功能。

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Osmosis-内分泌

This is called hypergonadotropic (because the level of gonadotropins are high) hypogonadism (because the level of gonad or ovarian hormones is low).

由于促腺激素水平高,而腺或卵巢激素水平低,这被称为高促腺激素型腺功能减退症

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Osmosis-内分泌

This leads to an overproduction of luteinizing and follicle stimulating hormones, so primary hypogonadism is also called hypergonadotropic hypogonadism.

这会导致LH和FSH生成过多,所以原腺功能减退症也称为高促腺激素腺功能减退症。

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Osmosis-内分泌

Though there are different causes which result in different levels of gonadotropin hormones, they all ultimately result in hypogonadism and a deficiency in testosterone or estrogen and progesterone.

尽管青春期延迟的病因很多,会导致促腺激素水平各不相同,但最终的结果都是功能减退以及男睾酮或女雌激素和孕酮的缺乏。

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Osmosis-内分泌

Just like in secondary hypogonadism, there's a lack of gonadotropin-releasing hormone, but the key difference is that it's not considered pathologic - instead, it's thought to be a naturally slowed rate of maturation.

与继功能减退症类似也存在GnRH的缺乏,但关键的区别在于这种缺乏不是病理的,而是一种正常的育延迟。

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Osmosis-内分泌

Secondary hypogonadism can be due to hypothalamus or pituitary gland dysfunction; either from an inability to produce gonadotropin-releasing hormone or luteinizing and follicle stimulating hormones, or suppression from other hormones, like prolactin or thyroid hormone.

功能减退症可由下丘脑或垂体功能障碍导致,既可能是促腺激素释放激素、黄体生成素和卵泡刺激素的生成能力低下,也可能是以上激素的分泌受到了其他激素的抑制,例如泌乳素或甲状腺激素。

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Osmosis-内分泌

The second cause of hypogonadism is secondary hypogonadism, which is also called hypogonadotropic hypogonadism because there are low levels of luteinizing and follicle stimulating hormones.

腺功能减退的第二个病因是继腺功能减退症,也称为低促腺素腺功能减退症,因为LH和FSH激素水平在此病中都显著降低。

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Osmosis-内分泌

The first is primary hypogonadism which is caused by dysfunction of the gonads - for example, the gonad's receptors may not respond to gonadotropin hormones, or the gonads might not have healthy cells that are capable of producing hormone.

一是原功能减退,由腺功能障碍引起,例如,腺受体对促腺激素不敏感或者腺内没有能够产生激素的健康细胞。

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