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Testicular allotransplantation is one of the effective options for the treatment of male infertility and hypogonadism.

异体是治疗男性不育或性腺功能减退方法之一

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Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属作供体行同种异体4例,其中医源性无症2例,原发性性腺机能低下2例,术后观察患者血清酮水平、第二性征变化及性功能情况

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Osmosis-生殖

Next, endocrine dysfunctions that causes testosterone levels to fall, like hypogonadism, can cause erectile dysfunction.

其次,内分泌碍导致睾酮水平下降,性腺减退会导致勃起碍。

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Osmosis-内分泌

Some acquired causes of primary hypogonadism are radiation therapy, chemotherapy, and trauma to the gonads.

可引起原发性性腺减退症的获得性素有放疗、化疗和性腺创伤。

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Osmosis-内分泌

Some congenital causes of primary hypogonadism are genetic diseases like Klinefelter or Turner syndrome.

可引起原发性性腺减退的先天素包括Klinefelter合征或Turner合征等遗传病。

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Osmosis-遗传

These streak ovaries can't produce sex hormones, resulting in hypogonadism and low estrogen levels.

这些条索状卵巢无法产生性激素,导致性腺低下、雌激素水平低。

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Osmosis-内分泌

Some acquired causes are similar to primary hypogonadism, radiation therapy, chemotherapy, and trauma to the gonads.

有些获得性素与原发性性腺减退症相似,也包括放疗、化疗和性腺创伤。

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Osmosis-内分泌

Because of this, Kallmann syndrome is a type of hypogonadotropic hypogonadism disorder.

,Kallmann合征是一种低促性腺激素性性腺减退症。

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Osmosis-内分泌

There are two main causes of hypogonadism.

性腺减退有两个主要病

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Osmosis-内分泌

Blood tests of hormone levels can give an idea of the type of hypogonadism.

血液激素水平的检测可以为性腺减退的类型提供参考

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Osmosis-内分泌

So, to recap: Kallmann syndrome is a type of hypogonadotropic hypogonadism where olfactory neurons and gonadotropin-releasing hormone neurons don't function normally.

Kallmann合征是一种低促性腺激素性性腺减退症,其嗅觉神经元与促性腺激素释放激素神经元不发挥正常

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Osmosis-内分泌

This is called hypergonadotropic (because the level of gonadotropins are high) hypogonadism (because the level of gonad or ovarian hormones is low).

由于促性腺激素水平高,而性腺或卵巢激素水平低,这被称为高促性腺激素型性腺减退症

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Osmosis-内分泌

This leads to an overproduction of luteinizing and follicle stimulating hormones, so primary hypogonadism is also called hypergonadotropic hypogonadism.

这会导致LH和FSH生成过多,所以原发性性腺减退症也称为高促性腺激素性性腺减退症。

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Osmosis-内分泌

Though there are different causes which result in different levels of gonadotropin hormones, they all ultimately result in hypogonadism and a deficiency in testosterone or estrogen and progesterone.

尽管青春期延迟的病很多,会导致促性腺激素水平各不相同,但最终的结果都是性腺减退以及男性睾酮或女性雌激素和孕酮的缺乏。

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Osmosis-内分泌

Just like in secondary hypogonadism, there's a lack of gonadotropin-releasing hormone, but the key difference is that it's not considered pathologic - instead, it's thought to be a naturally slowed rate of maturation.

与继发性性腺减退症类似也存在GnRH的缺乏,但关键的区别在于这种缺乏不是病理性的,而是一种正常的发育延迟。

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Osmosis-内分泌

Secondary hypogonadism can be due to hypothalamus or pituitary gland dysfunction; either from an inability to produce gonadotropin-releasing hormone or luteinizing and follicle stimulating hormones, or suppression from other hormones, like prolactin or thyroid hormone.

继发性性腺减退症可由下丘脑或垂体碍导致,既可是促性腺激素释放激素、黄体生成素和卵泡刺激素的生成力低下,也可是以上激素的分泌受到了其他激素的抑制,例泌乳素或甲状腺激素。

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Osmosis-内分泌

The second cause of hypogonadism is secondary hypogonadism, which is also called hypogonadotropic hypogonadism because there are low levels of luteinizing and follicle stimulating hormones.

性腺减退的第二个病是继发性性腺减退症,也称为低促性腺素性性腺减退症,为LH和FSH激素水平在病中都显著降低。

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Osmosis-内分泌

The first is primary hypogonadism which is caused by dysfunction of the gonads - for example, the gonad's receptors may not respond to gonadotropin hormones, or the gonads might not have healthy cells that are capable of producing hormone.

一是原发性性腺减退,由性腺碍引起,例,性腺受体对促性腺激素不敏感或者性腺内没有够产生性激素的健康细胞。

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