Eventually the pancreas gets damaged, because backed-up digestive enzymes degrade the cells lining the pancreatic ducts, causing local inflammation.

终胰腺受损，因为储备的消化酶降解了胰腺导管内的细胞，导致局限性炎症。

Cholecystokinin stimulates acinar cells in the pancreas to secrete digestive enzymes that travel through the pancreatic ducts and into the duodenum.

胆囊收缩素也能刺激胰腺的腺泡细胞产生消化酶；消化酶从胰腺导管排出，进十指肠。

This happens because thick secretions jam up the pancreatic ducts, not allowing digestive enzymes to make it to the small intestine.

因为粘稠的分泌物阻塞在胰腺导管中，使其无法被消化酶分解进小肠。

They found that it wasn't necessary to ligate a dog's pancreatic ducts in order to collect insulin.

他们发现没有必要结扎狗的胰管来收集胰岛素。

To digest a meal, these zymogens are released into the pancreatic duct, and delivered to the small intestine where they are activated by the protease trypsin.

当消化食物时，这些酶原被胰管，然后进小肠，在那里它们被胰蛋白酶激活。

Now, to prevent the hydrochloric acid from the stomach from damaging the intestinal mucosa, enteroendocrine cells also secrete another hormone, called secretin, which stimulates the pancreatic duct cells to secrete water and bicarbonate.

为了避免胃部产生的胃酸对小肠粘膜造成损伤，小肠内分泌细胞还可分泌胰泌素；它可以刺激胰腺导管细胞分泌水和碳酸氢盐。

It read, " Ligate pancreatic ducts of dogs." Banting's idea was to close off the small passages in a dog's pancreas that release its products into the rest of its body.

上面写着：“结扎狗的胰管。”班廷的想法是关闭狗胰腺中的小通道，这些通道将其产物到身体的其他部位。

When the pancreatic acinar cells are damaged or the the pancreatic ducts are blocked, often because of alcohol abuse or gallstones, the inactive zymogens that the pancreas produces can be prematurely converted to active digestive enzymes.

通常由酒精滥用或胆结石导致的胰腺腺泡细胞受损或胰管阻塞时，胰腺产生的无活性酶原可被过早转化为活性消化酶。