Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究表明粒体乙醛脱氢酶是体内催
硝
生物转
的主要
,
粒体乙醛脱氢酶同时具有脱氢酶和酯酶的催
活性,其酯酶活性可以通过将硝
脱硝形成一氧
氮,进而血管扩张。