In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生成协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌及增敏）药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛素、血小板、体内微量元素及促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例显示腰荐椎发育能是母亲糖尿所导致胚胎种，且无论有无接受胰岛素治疗，此先天畸形仍能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究研究焦点都在于胰岛素抵抗在糖耐量减低中作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿是慢性丙型肝炎（CHC）中纤维化进展以及对抗毒治疗无应答危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗能是腔隙性脑梗塞危险因素之。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A代谢产物视黄醛以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目观察比较二甲双胍与格列齐特对2型糖尿胰岛素抵抗(IR)及脂代谢紊乱疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表份报告表明，吸烟使人们患非胰岛素依赖型糖尿危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖以改善Ⅱ型糖尿小鼠胰岛细胞形态和功能并促进胰岛素分泌，有良好降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，论是含氧量正常还是在低氧培养条件下，小胰岛在体外胰岛素分泌方面由于大胰岛，并显示出相对较高存活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生成的协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌及增敏）的药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛素、血小板、体内微量元素及促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例荐椎发育不全可能是母亲糖尿所导致胚胎变的一种，且论有受胰岛素治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛素抵抗在糖耐量减低中的作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿是慢性丙型肝炎（CHC）中纤维化进展以及对抗毒治疗应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗可能是腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿胰岛素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖型糖尿的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿小鼠胰岛细胞形态和功能并促进胰岛素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小胰岛在体外胰岛素分泌方面由于大胰岛，并出相对较高的存活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄对脂肪生成协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重用（胰岛素促泌及增敏）药物适用T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

主要用体内代谢和产热、内源葡萄生成与胰岛素、血小板、体内微量元素及促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例显示腰荐椎发育不全可能是母亲尿所导致胚胎变一种，且无论有无接受胰岛素治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究研究焦点都在胰岛素抵抗在耐量减低用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和尿是慢性丙型肝炎（CHC）纤维化进展以及对抗毒治疗无应答危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗可能是腔隙性脑梗塞危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结表明，维生素A代谢产物视黄醛可以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目观察比较二甲双胍与格列齐特对2型尿胰岛素抵抗(IR)及脂代谢紊乱疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表一份报告表明，吸烟使人们患非胰岛素依赖型尿危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多可以改善Ⅱ型尿小鼠胰岛细胞形态和功能并促进胰岛素分泌，有良好降血用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结证明，不论是含氧量正常还是在低氧培养条件下，小胰岛在体外胰岛素分泌方面由大胰岛，并显示出相对较高存活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰和葡萄糖对脂肪生成的协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰量实验显示IUGR子鼠对外源性胰反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰促泌及增敏）的药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰、血小板、体内微量元及促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例显示腰荐椎育不全可能是母亲糖尿所导致胚胎变的一种，且无论有无接受胰治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰抵抗在糖量减低中的作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰促泌剂和胰增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰抵抗和糖尿是慢性丙型肝炎（CHC）中纤维化进展以及对抗毒治疗无应答的危险因。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰抵抗，胰抵抗可能是腔隙性脑梗塞的危险因之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生A的代谢产物视黄醛可以增加脂肪组织生成，降低胰敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿胰抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近表的一份报告表明，吸烟使人们患非胰依赖型糖尿的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿小鼠胰细胞形态和功能促进胰的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小胰在体外胰分泌方面由于大胰，显示出相对较高的存活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生成的协同效品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外源性胰岛素反迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌及增敏）的药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛素、血小板、体内微量元素及促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例显示腰荐椎发育不全可能是母亲糖尿所导致胚胎变的一种，且无论有无接受胰岛素治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都于胰岛素抵抗糖耐量减低中的作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明T2DM动物模型中，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休、脱水、高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿是慢性丙型肝炎（CHC）中纤维化进展以及对抗毒治疗无答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者胰岛素抵抗，胰岛素抵抗可能是腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿胰岛素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖型糖尿的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿小鼠胰岛细胞形态和功能并促进胰岛素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量常还是低氧培养条件下，小胰岛体外胰岛素分泌方面由于大胰岛，并显示出相对较高的活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，素和葡萄糖对脂肪生成的协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

素耐量实验显示IUGR子鼠对外源性素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有作用（素促泌及增敏）的药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与素、血小板、体内微量元素及促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

例显示腰荐椎发育不全可能是母亲糖尿所导致胚胎变的一种，且无论有无接受素治疗，先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因，横断面研究和前瞻性研究的研究焦点都在于素抵抗在糖耐量减低中的作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有素促泌剂和素增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

外，素抵抗和糖尿是慢性丙型肝炎（CHC）中纤维化进展以及对抗毒治疗无应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在素抵抗，素抵抗可能是腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲胍与格列齐特对2型糖尿素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表的一份报告表明，吸烟使人们患非素依赖型糖尿的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿小鼠细胞形态和功能并促进素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小在体外素分泌方面由于大，并显示出相对较高的存活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生成的协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素增敏）的药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛素、血小板、体内微量元素进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例显示腰荐椎发育不全可能是母亲糖尿所导致胚胎变的一种，且无论有无接受胰岛素治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛素抵抗在糖耐量减低的作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物，托吡酯同时有胰岛素剂和胰岛素增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿是慢性丙肝炎（CHC）纤维化进展以对抗毒治疗无应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗可能是腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2糖尿胰岛素抵抗(IR)脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖糖尿的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ糖尿小鼠胰岛细胞形态和功能并进胰岛素的分，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小胰岛在体外胰岛素分方面由于大胰岛，并显示出相对较高的存活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生成的协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量示IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌增敏）的药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛素、血小板、体内微量元素促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例示腰荐椎发育不全可能母亲糖尿所导致胚胎变的一种，且无论有无接受胰岛素治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛素抵抗在糖耐量减低中的作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖治疗关，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿慢性丙型肝炎（CHC）中纤维化进展以对抗毒治疗无应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗可能腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿胰岛素抵抗(IR)脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖型糖尿的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿小鼠胰岛细胞形态和功能并促进胰岛素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论含氧量正常还在低氧培养条件下，小胰岛在体外胰岛素分泌方面由于大胰岛，并示出相对较高的存活率。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，和葡萄对脂肪生成的协同效应存在品种差异。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

耐量实验显示IUGR子鼠对外源性反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（促泌及增敏）的药物适用于T2DM。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果主要用于体内代谢和产热、内源葡萄生成与、血小板、体内微量元及促进细胞有丝分裂和细胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此例显示腰荐椎发育不全可能母亲尿所导致胚胎变的一种，且无论有无接受疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于抵抗在耐量减低中的作用。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有促泌剂和增敏剂作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救的关键及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血疗关键，静滴极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，抵抗和尿慢性丙型肝炎（CHC）中纤维化进展以及对抗毒疗无应答的危险因。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在抵抗，抵抗可能腔隙性脑梗塞的危险因之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生A的代谢产物视黄醛可以增加脂肪组织生成，降低敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型尿抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行学杂志》最近发表的一份报告表明，吸烟使人们患非依赖型尿的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多可以改善Ⅱ型尿小鼠细胞形态和功能并促进的分泌，有良好的降血作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论含氧量正常还在低氧培养条件下，小在体外分泌方面由于大，并显示出相对较高的存活率。