1.Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
,有研究表明线粒体乙醛脱
酶是体内催
硝酸甘油生物转
的主要途径,线粒体乙醛脱
酶同时具有脱
酶和酯酶的催
活性,其酯酶活性可以通过将硝酸甘油脱硝形成一氧
,
而血管扩张。