Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究表明线粒乙醛脱酶是化硝酸甘油生物转化的主要途径,线粒乙醛脱酶同时具有脱酶和酯酶的化活,其酯酶活通过将硝酸甘油脱硝形成一氧化氮,进而血管扩张。