Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有明线粒体乙醛脱
酶是体内催化硝酸甘油生物转化的主要途径,线粒体乙醛脱
酶同时具有脱
酶和酯酶的催化活性,其酯酶活性可以通过将硝酸甘油脱硝形
化氮,进而血管扩张。